TY  - CHAP
M1  - Book, Section
TI  - Hereditary Nonpolyposis Colorectal Cancers
A1  - Dimopoulos, Christina
A1  - Llor, Xavier
A2  - Llor, Xavier
A2  - Hofstatter, Erin Wysong
PY  - 2022
T2  - Cancer Genetics: A Clinical Approach
AB  - Hereditary  colorectal  cancers,  both  polyposis  and  nonpolyposis,  arise  from  either  high-penetrance  germline  mutations  (such  as  in  mismatch  repair  genes  causing  Lynch  syndrome),  moderate-penetrance  genes  (such  as  CHEK2  or  the  APC  I1307  variant),  and  low-penetrance  alleles.  Nevertheless,  in  a  significant  number  of  cases  that  are  highly  suspicious  for  being  hereditary,  no  pathogenic  variants  are  identified  in  the  known  susceptibility  genes.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/16
UR  - hemonc.mhmedical.com/content.aspx?aid=1182365654
ER  -