TY - CHAP M1 - Book, Section TI - Pain Management and Symptom Control A1 - Shih, Kaoswi K. A1 - Dev, Rony A1 - Dalal, Shalini A2 - Kantarjian, Hagop M. A2 - Wolff, Robert A. A2 - Rieber, Alyssa G. PY - 2022 T2 - The MD Anderson Manual of Medical Oncology, 4e AB - KEY CONCEPTSPatients with cancer experience multiple symptoms that are often under-reported and not alleviated. Symptoms are often interrelated and can be both physical and/or psychological.Pain expression can be modified by cognitive and psychological factors associated with advanced disease or the dying process.A thorough psychosocial history, assessment of mental status, and screening with risk assessment tools for nonmedical opioid use is critical before prescribing opioid analgesics.Fatigue is the most common symptom in patients with advanced cancer and its treatment is challenging in later stages of disease. Patients and families benefit from education about the burdens of both physical and emotional fatigue. It can be helpful to modify daily activities and rest to accommodate for symptoms of fatigue as well as optimizing nutrition and hydration.Dyspnea is often an indicator of poor prognosis in advanced cancer. Initial management includes treating underlying causes medically when able. Palliative measures to reduce the sensation of air hunger include low flow supplemental oxygen for those with hypoxemia, opioids, or corticosteroids.Anorexia and weight loss are a result of systemic inflammation and inadequate caloric intake because of cancer and are often difficult to reverse. Psychosocial support for cachectic patients and their family caregivers can help diminish patient-family distress.Advanced care planning can decrease anxiety and suffering of patients and families as well as ensure autonomy for patients, especially if they become unable to express informed consent. However, it is an ongoing process that is best started early, revisited periodically, and incorporates room for change owing to unforeseen changes in the patient's clinical condition. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/04/24 UR - hemonc.mhmedical.com/content.aspx?aid=1190840650 ER -