TY - CHAP M1 - Book, Section TI - Marginal Zone B-Cell Lymphoma A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. PY - 2022 T2 - Williams Manual of Hematology, 10e AB - The marginal zone lymphomas (MZLs) are derived from memory-type or antigen-experienced B cells that reside in regions contiguous to the outer part of the mantle zones of B-cell folliclesMZL cells are usually small to medium-sized lymphocytes with irregularly shaped nuclei with dispersed chromatin and inconspicuous nucleoli.The World Health Organization (WHO) defines three separate MZL entities, namely, the extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (known as MALT lymphoma) (70%), the splenic marginal zone B-cell lymphoma (SMZL) (20%), and the nodal marginal zone B-cell lymphoma (NMZL) (<10%).Lymphoepithelial lesions characterized by invasion or necrotic destruction of the glandular epithelium by infiltrating lymphoma cells are characteristic of MALT lymphomas, especially those affecting the stomach.The WHO also recognize three provisional entities:— Extranodal marginal zone lymphoma (EMZL) of the MALT type.— Splenic marginal zone lymphoma (SMZL).— Nodal marginal zone lymphoma (NMZL). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/23 UR - hemonc.mhmedical.com/content.aspx?aid=1189335601 ER -