TY - CHAP M1 - Book, Section TI - Venous Thromboembolism A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. PY - 2022 T2 - Williams Manual of Hematology, 10e AB - Venous thromboembolism (deep venous thrombosis and/or pulmonary embolism) is a common disorder, which is estimated to affect 900,000 patients each year in the United States.Pulmonary embolism may cause sudden or abrupt death, underscoring the importance of prevention as the critical strategy for reducing death from pulmonary embolism.Of the estimated 600,000 cases of nonfatal venous thromboembolism in the United States each year, approximately 60% present clinically as deep venous thrombosis and 40% present as pulmonary embolism.Most clinically important pulmonary emboli arise from proximal deep venous thrombosis (thrombosis involving the popliteal, femoral, or iliac veins). Upper extremity deep venous thrombosis also may lead to clinically important pulmonary embolism. Other less common sources of pulmonary embolism include the deep pelvic veins, renal veins, inferior vena cava, right side of the heart, and axillary veins.Acquired and inherited risk factors for venous thromboembolism have been identified (Table 90–1). (For inherited thrombophilia, see Chap. 89.) The risk of thromboembolism increases when more than one predisposing factor is present. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1189336839 ER -