TY - CHAP M1 - Book, Section TI - Transfusion of Platelets A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. PY - 2022 T2 - Williams Manual of Hematology, 10e AB - Random donor platelets are prepared by centrifugation techniques that yield from 7 to 10 × 1010 platelets per unit of blood.Platelets so obtained are suspended in citrated autologous plasma and are significantly contaminated with leukocytes. Several units of platelets are pooled to provide sufficient platelets for transfusion (4–6 U for an adult).Single-donor platelets are prepared from a single individual by plateletpheresis. Each plateletpheresis contains approximately 3 to 4 × 1011 platelets, significantly contaminated with leukocytes, although more modern apheresis machines markedly reduce the level of white cell contamination in platelet concentrate.Fresh whole blood is used for platelet transfusion in children younger than 2 years of age who have undergone open heart surgery. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1189336957 ER -