TY - CHAP M1 - Book, Section TI - Pharmacotherapy of Inflammatory Bowel Disease A1 - MacNaughton, Wallace K. A1 - Sharkey, Keith A. A2 - Brunton, Laurence L. A2 - Knollmann, Björn C. PY - 2023 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition AB - AbbreviationsAPC: antigen-presenting cell5-ASA: 5-aminosalicylic acid, mesalamineCNS: central nervous systemCOX: cyclooxygenaseFDA: Food and Drug AdministrationGI: gastrointestinalGPCR: G protein-coupled receptorHGPRT: hypoxanthine-guanine phosphoribosyl transferaseHPA: hypothalamic-pituitary-adrenal (axis)5HT: 5-hydroxytryptamine (serotonin)IBD: inflammatory bowel diseaseIFN: interferonIL: interleukinJAK: Janus kinaseMAO: monoamine oxidase6-MMP: 6-methyl-mercaptopurineNE: norepinephrineNF-κB: nuclear factor-κBNSAID: nonsteroidal anti-inflammatory drugPPAR-γ: peroxisome proliferator-activated receptor gammaS1P: sphingosine-1-phosphateSTAT: signal transducer and activator of transcriptionTB: tuberculosisTGF: transforming growth factorTH: T helper (lymphocyte)TNF: tumor necrosis factorTPMT: thiopurine methyltransferaseTYK2: tyrosine kinase 2XO: xanthine oxidase SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1193238560 ER -