TY - CHAP M1 - Book, Section TI - Chemotherapy of Helminth Infections A1 - Keiser, Jennifer A1 - McCarthy, James A1 - Hotez, Peter A2 - Brunton, Laurence L. A2 - Knollmann, Björn C. PY - 2023 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition AB - Helminths are invertebrates featuring elongated, flat or round bodies. According to their morphology and the host organ they inhabit, they are classified as flatworms or platyhelminths, which include flukes (lung flukes [Paragonimus spp.], liver flukes [Fasciola spp., Clonorchis sinensis, Opisthorchis spp.], intestinal flukes, or blood flukes [Schistosoma spp.]), tapeworms (cestodes [including Taenia solium, T. saginata], Diphyllobothrium latum, Hymenolepis nana, and Echinococcus spp.), and roundworms (nematodes). The nematodes of major medical importance include the soil-transmitted helminths (STHs) (Ascaris lumbricoides, Trichuris trichiura, Necator americanus, Ancylostoma duodenale, Strongyloides stercoralis) and the filarial worms. Lymphatic filariasis is caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori. Subcutaneous filariasis is caused by Loa loa, Mansonella streptocerca, and Onchocerca volvulus. Mansonella perstans and Mansonella ozzardi are the causative helminths for serous cavity filariasis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1193241382 ER -