TY - CHAP M1 - Book, Section TI - Goodman & Gilman Year in Review New and Noteworthy FDA Approvals A1 - Murri, Nelda A2 - Brunton, Laurence L. A2 - Knollmann, Björn C. PY - 2023 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition AB - AbbreviationsAAV: adeno-associated virusaTTP: acquired thrombotic thrombocytopenic purpuraADC: antibody–drug conjugateASO: antisense oligonucleotideATTR: transthyretin amyloidosisATTR-CM: transthyretin amyloid cardiomyopathyBCRP: breast cancer–resistant proteinBLAs: biologic license applicationsCAR: chimeric antigen receptorFDA: U.S. Food and Drug AdministrationFGFR: fibroblast growth factorGST: glutathione S transferasehATTR-PM: polyneuropathy manifestations of hereditary ATTRHRSA: Health Resources and Services AdministrationHSDD: hypoactive sexual desire disorderLRP: lipoprotein-related proteinMCR: melanocortin receptorMMAE: monomethyl auristatin E (vedotin)NDA: new drug applicationNES: nuclear export signalOA: onasemnogene abeparvovecPV: polatuzumab vedotinscAAV9: self-complementary AAV serotype 9sd: single-domainsdAb: single-domain antibody fragmentsSINE: selective inhibitor of nuclear exportsiRNA: small interfering double-stranded ribonucleic acidSMA: spinal muscular atrophySMN: survival motor neuronTTR: transthyretinUGT: UDP–glucuronosyltransferasevWF: von Willebrand factorWnt: wingless-type mouse mammary virus integration siteXPO1: exportin 1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/05 UR - hemonc.mhmedical.com/content.aspx?aid=1198878765 ER -