TY - CHAP M1 - Book, Section TI - Vaginal Cancer A1 - Lowery, William J. A1 - Chino, Junzo A1 - Havrilesky, Laura J. A2 - Karlan, Beth Y. A2 - Bristow, Robert E. A2 - Li, Andrew J. PY - 2015 T2 - Gynecologic Oncology: Clinical Practice and Surgical Atlas AB - Primary vaginal cancer is an uncommon gynecologic malignancy and constitutes only 1% to 2% of gynecologic malignancies. Because of its rarity, there are specific guidelines for the diagnosis of primary vaginal cancer. A malignancy located in the vagina and not involving any adjacent pelvic organs is considered to be a primary vaginal cancer. If the malignancy extends to the cervix or vulva, it is considered a primary lesion of the nonvaginal site. Based on the observation that 95% of patients with recurrent cervical cancer will experience relapse within 5 years, all squamous cell carcinomas identified in the vagina within this period are defined as recurrences. Only those squamous cell carcinomas found more than 5 years after the diagnosis of cervical cancer are defined as primary vaginal cancers.1 If there is a history of endometrial cancer, a diagnosis of adenocarcinoma in the vagina is usually considered a recurrence regardless of the time from primary treatment. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1106570660 ER -