TY - CHAP M1 - Book, Section TI - Targeted Therapy and Immunotherapy A1 - Coleman, Robert L. A1 - Sabbatini, Paul J. A2 - Karlan, Beth Y. A2 - Bristow, Robert E. A2 - Li, Andrew J. PY - 2015 T2 - Gynecologic Oncology: Clinical Practice and Surgical Atlas AB - While simplistic in its view, the effectors of the immune system are generally divided into those components that support innate immunity and those that support acquired immunity. The classification suggests a dichotomous relationship, but there is necessary and frequent cross-talk between the 2 arms. Innate immunity is active from birth, is the first line of defense against most pathogens, and does not require modification for activity. Acquired immunity largely requires activation of B lymphocytes and T lymphocytes and uses a complex process of activation, modification, expansion, and suppression in response to changing stimuli. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1106572124 ER -