TY - CHAP M1 - Book, Section TI - Erythropoietic Effects of Endocrine Disorders A1 - Gregg, Xylina T. A2 - Kaushansky, Kenneth A2 - Lichtman, Marshall A. A2 - Prchal, Josef T. A2 - Levi, Marcel M. A2 - Press, Oliver W. A2 - Burns, Linda J. A2 - Caligiuri, Michael PY - 2015 T2 - Williams Hematology, 9e AB - SUMMARYAnemia is the most common hematopoietic abnormality in endocrine disorders and may be the first manifestation of an endocrine disorder. Polycythemia/erythrocytosis is less common, but occurs in certain endocrine disorders. The pathophysiologic basis of the anemia is often multifactorial, but a direct influence of hormones on erythropoiesis in some instances may contribute to anemia. A decreased plasma volume in some of these disorders may mask the severity of anemia. It has been proposed that anemia in endocrine-deficiency states may be physiologic to adjust for decreased oxygen requirements. Some endocrine disorders are associated with an impaired response to the therapeutic use of erythropoietin. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1121091974 ER -