TY - CHAP M1 - Book, Section TI - Drug-Induced Hemolytic Anemia A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Kipps, Thomas J. A1 - Prchal, Josef T. A1 - Levi, Marcel M. Y1 - 2011 N1 - T2 - Williams Manual of Hematology, 8e AB - Table 26–1 lists the drugs implicated in the production of a positive direct antiglobulin test and accelerated red cell destruction.Three mechanisms of drug-related immunologic injury to red cells are defined:— Hapten/drug adsorption involving drug-dependent antibodies.— Ternary complex formation involving drug-dependent antibodies.— Induction of autoantibodies that react with red cells in the absence of the inciting drug.Drug-related nonimmunologic protein adsorption may also result in a positive direct antiglobulin test without red cell injury. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1126651742 ER -