TY  - CHAP
M1  - Book, Section
TI  - Pharmacology and Toxicity of Antineoplastic Drugs
A1  - Lichtman, Marshall A.
A1  - Kaushansky, Kenneth
A1  - Kipps, Thomas J.
A1  - Prchal, Josef T.
A1  - Levi, Marcel M.
Y1  - 2011
N1  - 
T2  - Williams Manual of Hematology, 8e
AB  - Knowledge  of  drug  actions,  pharmacokinetics,  clinical  toxicities,  and  drug  interactions  is  essential  for  the  proper  and  safe  administration  of  cancer  chemotherapy.Use  established  regimens,  and  recheck  doses.Choice  of  a  particular  drug  treatment  program  should  depend  on  the  disease,  histology,  and  stage  of  the  disease  and  on  an  assessment  of  individual  patient  tolerance.High-dose  chemotherapy  programs  used  in  autologous  and  allogeneic  hematopoietic  stem  cell  transplantation  result  in  additional  organ  toxicities  that  are  not  seen  at  conventional  doses.Chemotherapy  usually  targets  process  of  DNA  replication.More  recently,  drugs  have  been  introduced  to  target  specific  cellular  processes,  including  receptor  signaling,  inhibition  of  oncoproteins,  angiogenesis,  and  membrane  cluster  of  differentiation  antigens.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - hemonc.mhmedical.com/content.aspx?aid=1126652419
ER  -