TY - CHAP M1 - Book, Section TI - General Anesthetics and Therapeutic Gases A1 - Hilal-Dandan, Randa A1 - Brunton, Laurence L. Y1 - 2016 N1 - T2 - Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e AB - General anesthetics depress the central nervous system to a sufficient degree to permit the performance of surgery and unpleasant procedures. General anesthetics have low therapeutic indices and thus require great care in administration. The selection of specific drugs and routes of administration to produce general anesthesia is based on their pharmacokinetic properties and on the secondary effects of the various drugs, in the context of the proposed diagnostic or surgical procedure and with the consideration of the individual patient's age, and associated medical condition. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - hemonc.mhmedical.com/content.aspx?aid=1127549304 ER -