TY - CHAP M1 - Book, Section TI - Interferons A1 - Longo, Dan L. A2 - Chabner, Bruce A. A2 - Longo, Dan L. Y1 - 2016 N1 - T2 - Harrison's Manual of Oncology, 2e AB - The interferons (IFNs) are a family of proteins that are grouped into three classes α, β, and γ. They were discovered based on their ability to "interfere" with viral infection of cells. Subsequent study has revealed a panoply of biological actions including immunomodulatory, antiproliferative, and antiangiogenic effects (1). Nearly all the oncologic applications of the IFNs have been of the α class. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - hemonc.mhmedical.com/content.aspx?aid=1127646860 ER -