TY - CHAP M1 - Book, Section TI - Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma A1 - Amrein, Philip C. A2 - Chabner, Bruce A. A2 - Longo, Dan L. Y1 - 2016 N1 - T2 - Harrison's Manual of Oncology, 2e AB - Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of monoclonal lymphocytes in blood, bone marrow, and lymphoid tissues. These lymphocytes are small, mature-appearing B cells typically expressing CD19, CD5, and CD23. It is generally a disease of older people and prognosis ranges widely from a few years to many years, but it is not considered curable outside of the bone marrow transplant setting. At times these neoplastic cells predominate in lymph nodes leading to the classification as a lymphoma. Hence, the WHO in 2008 has defined this neoplasm as chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (1). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - hemonc.mhmedical.com/content.aspx?aid=1127647973 ER -