TY - CHAP M1 - Book, Section TI - Peripheral T-cell Lymphomas A1 - Barnes, Jeffrey A. A1 - Abramson, Jeremy S. A2 - Chabner, Bruce A. A2 - Longo, Dan L. Y1 - 2016 N1 - T2 - Harrison's Manual of Oncology, 2e AB - The peripheral T-cell lymphomas are a heterogeneous group of lymphoid malignancies each with a distinct clinical presentation and prognosis. The term "peripheral" denotes mature T-cell neoplasms, differentiating them from the precursor lymphoid diseases T-cell acute lymphoblastic leukemia and lymphoblastic lymphoma. Treatment regimens for peripheral T-cell lymphomas are generally derived from data extrapolated from trials of aggressive non-Hodgkin lymphoma (NHL) before the advent of CD20-directed therapies of which T-cell lymphomas represent approximately 10% of the studied population. While therapies are often overlapping, T-cell lymphomas in general have an inferior prognosis to their B-cell counterparts. Recent advances have been made, however, with development of treatments specifically directed at peripheral T-cell lymphomas. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1127648312 ER -