TY  - CHAP
M1  - Book, Section
TI  - Primary Squamous Carcinoma of the Uterine Cervix: Diagnosis and Management
A1  - Foley, Olivia
A1  - del Carmen, Marcela G.
A2  - Chabner, Bruce A.
A2  - Longo, Dan L.
Y1  - 2016
N1  - 
T2  - Harrison's Manual of Oncology, 2e
AB  - Squamous  cell  carcinoma  of  the  uterine  cervix  comprises  an  estimated  80%  of  all  cervical  cancers.  The  other  histologies  include  adenocarcinoma  (15%)  and  adenosquamous  carcinomas  (3%–5%),  with  only  a  small  fraction  of  all  cervical  cancers  having  neuroendocrine  or  small  cell  histology.  This  chapter  will  focus  on  the  diagnosis  and  management  of  primary  squamous  cell  carcinoma  of  the  uterine  cervix.  Amongst  all  malignancies,  cervical  cancer  is  the  second  most  common  cancer  affecting  women,  with  an  estimated  52%  case-fatality  rate  (1).  Worldwide,  cervical  cancer  is  the  most  common  gynecologic  malignancy,  accounting  for  529,800  new  cases  (9%)  and  273,200  deaths  (8%)  (1,  2).  In  developed  countries,  cervical  cancer  ranked  tenth  most  common  type  of  cancer  in  women  (9.0/100,000  women)  and  below  the  top  10  causes  of  cancer  mortality  (3.2/100,000  deaths)  (3).  An  estimated  86%  of  new  cervical  cancer  cases  are  seen  in  the  developing  world,  ranking  as  the  second  most  common  type  of  cancer  (17.8/100,000  women)  and  cause  of  cancer  deaths  (99.8/100,000  deaths)  (3).  The  highest  incidence  rates  worldwide  are  observed  in  sub-Saharan  Africa,  Latin  America  and  the  Caribbean,  South-Central  Asia,  and  Southeast  Asia  (1).  One-third  of  the  cervical  cancer  burden  in  the  world  is  experienced  in  South-Central  Asia.  Lastly,  although  cervical  cytology  is  an  excellent  screening  instrument  for  pre-invasive  disease,  the  false  negative  rate  for  detecting  invasive  carcinoma  is  relatively  high,  reportedly  50%.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - hemonc.mhmedical.com/content.aspx?aid=1127649417
ER  -