TY - CHAP M1 - Book, Section TI - HEMOCHROMATOSIS A1 - Hillman, Robert S. A1 - Ault, Kenneth A. A1 - Leporrier, Michel A1 - Rinder, Henry M. Y1 - 2016 N1 - T2 - Hematology in Clinical Practice, 5e AB - CASE HISTORY • Part 1A 47-year-old man presents with palpitations, shortness of breath, and marked asthenia. Past history and review of systems (ROS) are positive for more than 10 years of arthralgia/arthritis of both small and large joints, progressive loss of libido, and recent weight loss. Vital signs: BP - 135/80 mm Hg, P - 96 bpm, R - 16 bpm. Examination reveals a tanned, anxious white male; irregular pulse without cardiomegaly or murmurs; slight hepatomegaly; no obvious joint deformity; and testicular atrophy. Initial studies:CBC: Hematocrit/hemoglobin - 42%/14 g/dLMCV - 90 fL MCH - 32 pg MCHC - 33 g/dLWhite blood cell count - 7,200 /μL with a normal differentialPlatelet count - 190,000/μLSMEAR MORPHOLOGYNormocytic and normochromic with normal white cell morphology.Reticulocyte count/index - 1%/1.0Blood chemistries: Fasting glucose - 150 mg/dLSlightly elevated AST and ALTSerum iron - 270 μg/dL TIBC - 300 μg/dLSerum ferritin - 2,360 μg/LECG - Atrial fibrillation, left bundle hemiblock and strain patternQuestionsGiven the patient's history and laboratory findings, what diagnosis comes to mind?What additional laboratory tests are indicated? SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1127766730 ER -