TY - CHAP M1 - Book, Section TI - Classification and Clinical Manifestations of the Malignant Lymphoid Disorders A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. Y1 - 2017 N1 - T2 - Williams Manual of Hematology, 9e AB - Lymphocyte malignancies comprise a wide spectrum of different morphologic and clinical syndromes.The International Lymphoma Study Group proposed a new classification termed Revised European–American Lymphoma classification, or REAL classification, which was modified in 2001 and updated in 2008 by the World Health Organization (WHO) (see Table 53–1).The REAL/WHO classification makes use of the pathologic, immunophenotypic, genetic, and clinical features to define separate disease entities (Table 53–1).Lymphocytic neoplasms are divided into those derived from B cells, T cells, or natural killer (NK) cells.The immunophenotype and the characteristic cytogenetic and genic abnormalities are also included in Table 53–1.The most common indolent and aggressive lymphocytic neoplasms, based on their usual clinical behavior, are listed in Tables 53–2 and 53–3. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1133364650 ER -