TY - CHAP M1 - Book, Section TI - Lobular Carcinoma in Situ and Lobular Neoplasia A1 - King, Tari A. A1 - Reis-Filho, Jorge S. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. Y1 - 2018 N1 - T2 - Textbook of Complex General Surgical Oncology AB - The term lobular neoplasia (LN) encompasses the entire spectrum of atypical epithelial lesions that originate in the terminal duct-lobular unit (TDLU) of the breast, and are characterized by a population of dyshesive cells, which expand the lobules and acini of the TDLUs, and may involve the terminal ducts in a pattern known as Pagetoid spread.1 These lesions were traditionally described under the terms lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH), which refer to the degree of involvement of the acinar structures of a given TDLU. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1145760105 ER -