TY  - CHAP
M1  - Book, Section
TI  - Metastatic Colorectal Cancer
A1  - Lynn, Patricio B.
A1  - Keskin, Metin
A1  - Garcia-Aguilar, Julio
A2  - Morita, Shane Y.
A2  - Balch, Charles M.
A2  - Klimberg, V. Suzanne
A2  - Pawlik, Timothy M.
A2  - Posner, Mitchell C.
A2  - Tanabe, Kenneth K.
Y1  - 2018
N1  - 
T2  - Textbook of Complex General Surgical Oncology
AB  - Metastasis  is  defined  as  the  spread  of  malignant  cells  from  a  primary  tumor  to  a  distant  organ.  It  is  estimated  that  90%  of  all  cancer  deaths  are  a  result  of  metastasis.1  Colorectal  cancer  (CRC)  can  metastasize  to  regional  lymph  nodes,  liver,  lung,  or  the  peritoneal  surface,  and  less  frequently  to  other  organs  such  as  ovaries,  brain,  and  bone.  While  CRC  with  locoregional  lymphatic  spread  is  categorized  as  stage  III  disease  (5-year  overall  survival  (OS)  70.4%),  CRC  with  spread  to  distant  organs  is  categorized  as  stage  IV—or  metastatic—CRC  (CRCm)  and  carries  a  significantly  worse  prognosis  (5-year  OS  12.3%).2  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - hemonc.mhmedical.com/content.aspx?aid=1145762934
ER  -