TY - CHAP M1 - Book, Section TI - Distal Cholangiocarcinoma and Periampullary Cancer A1 - Hameed, S. Morad A1 - Dixon, Elijah A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. Y1 - 2018 N1 - T2 - Textbook of Complex General Surgical Oncology AB - Located deep within the surgical soul, and surrounded by a forest of critical structures, cancers of the distal biliary tract and periampullary region are difficult to diagnose, and even more difficult to treat. They demonstrate aggressive biology and they present late, features that often make them unmanageable, and even uniformly fatal. However, advances in our understanding of molecular genetics, diagnostic imaging, surgical technique, neoadjuvant and adjuvant therapies, and palliative care have opened new options for the care of patients with these malignancies. Scientific advances over the next few years will place us on an exciting new frontier in the journey to successfully address what has been one of surgery’s greatest challenges. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1145764425 ER -