TY - CHAP M1 - Book, Section TI - Myeloproliferative Neoplasms and Myelodysplastic Syndromes A1 - Aster, Jon C. A1 - Steensma, David P. A2 - Aster, Jon C. A2 - Bunn, H. Franklin Y1 - 2016 N1 - T2 - Pathophysiology of Blood Disorders, 2e AB - LEARNING OBJECTIVESAfter studying this chapter, you should understand:The pathogenic role of specific tyrosine kinase mutations in various myeloproliferative neoplasms.The role of BCR-ABL in the diagnosis and targeted therapy of chronic myelogenous leukemia.The diagnostic and pathogenic role of JAK2 mutations in polycythemia vera.The diagnostic and pathogenic roles of JAK2, calreticulin and thrombopoietin receptor mutations in essential thrombocytosis and primary myelofibrosisThe pathophysiology and clinical features of the myelodysplastic syndromes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1175525434 ER -