TY - CHAP M1 - Book, Section TI - Positioning Yourself for a Successful MD-PhD Application A1 - Vasavda, Chirag A1 - Hinkle, Jared A2 - Eisenberg, Mark J. A2 - Cox, Andrea L. Y1 - 2021 N1 - T2 - The Essential MD-PhD Guide AB - Chirag Vasavdaentered the MD-PhD program at Johns Hopkins University in 2014. He joined the Biochemistry, Cellular and Molecular Biology graduate program and studied under Dr. Solomon Snyder in the Department of Neuroscience. In graduate school, he discovered that the heme metabolite bilirubin binds and activates the orphan receptor MRGPRX4 in itch sensory neurons, potentially contributing to itch in hepatobiliary disease. He also identified that bilirubin is a physiologic antioxidant with distinct redox activity that negatively regulates superoxide signaling during neurotransmission. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/04/18 UR - hemonc.mhmedical.com/content.aspx?aid=1179534928 ER -