TY - CHAP M1 - Book, Section TI - Eosinophils and Their Disorders A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. Y1 - 2022 N1 - T2 - Williams Manual of Hematology, 10e AB - Eosinophil progenitors originate directly from the common myeloid progenitor after acquisition of interleukin (IL)-5 receptor alpha.Differentiation is regulated by the transcription factors C/EBP-A and GATA-1 in addition to other factors such as GATA-2, PU.1, and FOG-1.The normal adult marrow contains approximately 3% eosinophils.Eosinophils differentiate in the marrow, migrate into the blood, and circulate for 25 hours before entering tissues. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1189333952 ER -