TY - CHAP M1 - Book, Section TI - The Mononucleosis Syndromes A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. Y1 - 2022 N1 - T2 - Williams Manual of Hematology, 10e AB - Infectious mononucleosis is defined as any blood lymphocytosis induced in response to an infectious agent.Usually greater than 50% of the circulating white cells are lymphocytes, more than 10% of which have the morphology of reactive lymphocytes (Figure 53–1).Table 53–1 lists the etiologic agents that produce mononucleosis.Pharyngeal form:— A sore throat is preceded by 1 to 2 weeks of lethargy.— Epstein-Barr virus (EBV) generally is the cause.Glandular form without pharyngitis:— Lymph node enlargement occurs.— The usual cause is an agent other than EBV (eg, Toxoplasma gondii).Typhoidal form:— Lethargy with fever or diarrhea without pharyngitis, usually as a consequence of cytomegalovirus (CMV). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1189335108 ER -