TY - CHAP M1 - Book, Section TI - Classification and Clinical Manifestations of the Neoplastic Lymphocytic Disorders A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. Y1 - 2022 N1 - T2 - Williams Manual of Hematology, 10e AB - Lymphocyte malignancies comprise a wide spectrum of different morphologic and clinical syndromes.The International Lymphoma Study Group proposed a new classification termed the Revised European–American Lymphoma classification, or REAL classification, which was modified in 2001 and updated in 2008 and in 2016 by the World Health Organization (WHO) (Table 54–1).The WHO classification makes use of the pathologic, immunophenotypic, genetic, and clinical features to define separate disease entities (Table 54–1).Lymphocytic neoplasms are divided into those derived from B cells, T cells, or natural killer (NK) cells.The immunophenotype and the characteristic cytogenetic and genic abnormalities are also included in Table 54–1.The most common indolent and aggressive lymphocytic neoplasms, based on their usual clinical behavior, are listed in Tables 54–2 and 54–3. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1189335128 ER -