TY - CHAP M1 - Book, Section TI - Cancer in Pregnancy A1 - Amneus, Malaika A1 - Holschneider, Christine H. A2 - Karlan, Beth Y. A2 - Bristow, Robert E. A2 - Li, Andrew J. Y1 - 2015 N1 - T2 - Gynecologic Oncology: Clinical Practice and Surgical Atlas AB - The diagnosis of cancer complicates approximately 1 in 1000 pregnancies. Once diagnosed, emotional, ethical, diagnostic, and treatment dilemmas confront both the patient and the treating physicians, posing unique challenges. Questions regarding whether or not to terminate the pregnancy, potential maternal risk of delays in cancer treatment, fetal risks of early delivery, and maternal and fetal effects of cancer treatments during gestation are complex and competing factors that make decision making both medically and emotionally challenging. Limited data on the treatment of malignancies during pregnancy and absence of randomized controlled studies in this population contribute to the lack of generalized treatment algorithms. Individualization of treatment planning with a multidisciplinary team is essential. Considerations not only include the risk/benefit assessment of treatment modalities such as chemotherapy, radiation therapy, and surgery during pregnancy, but also include the potential maternal and fetal consequences of diagnostic procedures. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/10/06 UR - hemonc.mhmedical.com/content.aspx?aid=1106571420 ER -