TY - CHAP M1 - Book, Section TI - Hemoglobinopathies Associated with Unstable Hemoglobin A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Kipps, Thomas J. A1 - Prchal, Josef T. A1 - Levi, Marcel M. PY - 2011 T2 - Williams Manual of Hematology, 8e AB - The unstable hemoglobins discussed here result from a mutation that changes the amino acid sequence of one of the globin chains, leading to instability and precipitation of the hemoglobin molecule.Homotetramers of normal β chains (hemoglobin H) or γ chains (hemoglobin Bart's) are also unstable. These hemoglobins are found in α-thalassemia (see Chap. 16). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1126651537 ER -