TY  - CHAP
M1  - Book, Section
TI  - Reactive (Secondary) Thrombocytosis
A1  - Lichtman, Marshall A.
A1  - Kaushansky, Kenneth
A1  - Kipps, Thomas J.
A1  - Prchal, Josef T.
A1  - Levi, Marcel M.
PY  - 2011
T2  - Williams Manual of Hematology, 8e
AB  - The  upper  limit  of  a  normal  platelet  count  is  usually  between  350  ×  109/L  and  450  ×  109/L  depending  on  the  clinical  laboratory  and  specific  method  used.Table  75–1  presents  the  major  causes  of  elevation  of  the  platelet  count  above  the  normal  limit.Reactive  thrombocytosis  may  persist  for  prolonged  periods  and  resolve  only  with  resolution  of  the  underlying  disorder.Thrombocytosis  after  recovery  from  thrombocytopenia  ("rebound")  usually  peaks  in  10  to  14  days.The  platelet  count  after  splenectomy  may  reach  1000  ×  109/L  or  more  within  the  first  week  and  return  to  normal  within  about  2  months.  Severe  or  persistent  postsplenectomy  thrombocytosis  may  be  a  result  of  persistent  iron  deficiency  anemia  or  unmasking  of  primary  thrombocythemia.There  is  no  convincing  evidence  that  therapy  to  reduce  the  platelet  count  or  interfere  with  platelet  function  is  of  benefit  in  reactive  thrombocytosis,  with  the  possible  exception  of  severe  postsplenectomy  thrombocytosis  in  patients  with  persistent  hemolytic  anemia.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - hemonc.mhmedical.com/content.aspx?aid=1126654319
ER  -