TY - CHAP M1 - Book, Section TI - EXTRINSIC AND COMMON PATHWAY COAGULOPATHIES A1 - Hillman, Robert S. A1 - Ault, Kenneth A. A1 - Leporrier, Michel A1 - Rinder, Henry M. PY - 2016 T2 - Hematology in Clinical Practice, 5e AB - CASE HISTORY • Part 1A 71-year-old woman presents with 1 day of headache and left-sided weakness after complaining for several days of dyspnea and confusion. Her history is notable for non-valvular atrial fibrillation and hypertension; she denies any prior history of thrombosis or bleeding. Her medications include a beta-blocker and warfarin (coumadin). Examination is notable for partial left hemiplegia; ecchymoses are noted over both forearms. The remainder of the examination demonstrates rales over both lung bases, an irregularly irregular heart rhythm, and a heave at the left sternal border.CBC: Hemoglobin/hematocrit - 12 g/dL/35%MCV - 89 fL MCH - 30 pg MCHC - 27 g/dLRDW-CV - 10% WBC count 6,500/μLPlatelet count - 225,000/μLPT = 55.1 seconds (<14 seconds)INR = 7.1 (<1.3)PTT = 39 seconds (22–35 seconds)QuestionsDo the screening coagulation test results point to a specific cause for a bleeding tendency in this patient?Are additional studies warranted for diagnosis or determining therapy? SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1127768601 ER -