TY  - CHAP
M1  - Book, Section
TI  - Guidelines for Chemotherapy Dosage Adjustment
A1  - McDevitt, Pamela W.
A1  - Fojo, Tito
A2  - Boyiadzis, Michael M.
A2  - Frame, James N.
A2  - Kohler, David R.
A2  - Fojo, Tito
PY  - 2016
T2  - Hematology-Oncology Therapy, 2e
AB  - Table  Graphic  Jump  Location|Download  (.pdf)|PrintAlphabetical  Listing  of  Drugs  by  both  Generic  (bold)  and  Proprietary  NamesDrug  Names:  Generic  (in  bold)  or  ProprietaryDrug  Names:  Generic  (in  bold)  or  ProprietaryAdjust  if  Function  ImpairedHepaticRenalAbiraterone  acetateZytiga®+−Abraxane®Paclitaxel  protein  bound  particles+−Adcetris™Brentuximab  vedotin−−ado-trastuzumab  emtansineKadcyla™±±Adriamycin®Doxorubicin  HCl+−AfatinibGilotrif±±Afatinib  dimaleateGilotrif™±±Afinitor®Everolimus+±Agrylin®Anagrelide  HCl+−AldesleukinProleukin®−+AlemtuzumabCampath®−−Alimta®Pemetrexed  disodium−±AlitretinoinPanretin®−−Alkeran®Melphalan  (orMelphalan  HCl)−+AltretamineHexalen®−−AmifostineEthyol®−−AminoglutethimideCytadren®−−AmsacrineAmsidine®++Amsidine®Amsacrine++Anagrelide  HClAgrylin®+−AnastrozoleArimidex®+−Aranesp®Darbepoetin  alfa−−Aredia®Pamidronate  disodium±+Arimidex®Anastrozole+−Aromasin®Exemestane−−Arranon®Nelarabine±±Arsenic  trioxideTrisenox™++Arzerra™Ofatumumab−−Asparaginase  (E.  coli  source)Elspar®±±Asparaginase  (Erwinia  chrysanthemi  source)Erwinaze™±±Atralin™Tretinoin++Avastin®Bevacizumab−−AxitinibInlyta®±±AzacitidineVidaza®++Bendamustine  HClTreanda®++BevacizumabAvastin®−−BexaroteneTargretin®±±Bexxar®Tositumomab−±BicalutamideCasodex®±−BiCNU®Carmustine±+Blenoxane®Bleomycin  sulfate±+Bleomycin  sulfateBlenoxane®±+BortezomibVelcade®+±Bosulif®Bosutinib±±BosutinibBosulif®±±Brentuximab  vedotinAdcetris™−−Buserelin  acetateSuprefact®−−BusulfanBusulfex®±−Busulfex®Busulfan±−CabazitaxelJevtana®±±CabozantinibS-malateCometriq™±±Campath®Alemtuzumab−−Camptosar®Irinotecan  HCl+−CapecitabineXeloda®±+Caprelsa®Vandetanib±+CarboplatinParaplatin−AQ®−+CarfilzomibKyprolis™±−CarmustineBiCNU®±+Casodex®Bicalutamide±−CeeNU®Lomustine±+Cerubidine®Daunorubicin  HCl++CetuximabErbitux®−−ChlorambucilLeukeran®±+CisplatinPlatinol®−+CladribineLeustatin®±+ClofarabineClolar®±±Clolar®Clofarabine±±Cometriq™CabozantinibS-malate±±Cosmegen®Dactinomycin±−CrizotinibXalkori®±±Cytadren®Aminoglutethimide−−CytarabineCytosar-U®++Cytarabine  lipid  complex  (liposome)DepoCyt®−−Cytosar-U®Cytarabine++DabrafenibTafinlar±±Dabrafenib  mesylateTafinlar®±±DacarbazineDTIC-Dome®±+Dacogen™Decitabine±±DactinomycinCosmegen®±−Denileukin  diftitoxOntak®−−DenosumabXgeva®±±Darbepoetin  alfaAranesp®−−DasatinibSprycel®±±Daunorubicin  HClCerubidine®++Daunorubicin  citrate  liposomalDaunoXome®++DaunoXome®Daunorubicin  citrate  liposomal++DecitabineDacogen™±±DepoCyt®Cytarabine  lipid  complex  (liposome)−−Dexrazoxane  HClTotect®,  Zinecard®−+DocetaxelTaxotere®+−Doxil®Doxorubicin  HCl  liposomal+−Doxorubicin  HClAdriamycin®+−Doxorubicin  HCl  liposomalDoxil®+−Droxia®Hydroxyurea±+DTIC-Dome®Dacarbazine±+Ellence®Epirubicin  HCl++Eloxatin®Oxaliplatin−+Elspar®Asparaginase  (E.  coli  source)±±Emcyt®Estramustine  phosphate  sodium−−EnzalutamideXtandi®±±Epirubicin  HClEllence®++Epoetin  alfaProcrit®−−Erbitux®Cetuximab−−Eribulin  mesylateHalaven™++Erivedge®Vismodegib±±Erlotinib  HClTarceva®+−Erwinaze™Asparaginase  (Erwinia  chrysanthemi  source)±±Estramustine  phosphate  sodiumEmcyt®−−Ethyol®Amifostine−−Etopophos®Etoposide  phosphate++EtoposideVePesid®++Etoposide  phosphateEtopophos®++Eulexin®Flutamide−−EverolimusAfinitor®+±Evista®Raloxifene  HCl±±ExemestaneAromasin®−−Fareston®Toremifene  citrate−−Faslodex®Fulvestrant+−Femara®Letrozole+−FilgrastimNeupogen®−−FloxuridineFUDR®+±Fludara®Fludarabine±+FludarabineFludara®±+FluorouracilFluorouracil±±FluorouracilFluorouracil±±FluoxymesteroneHalotestin®−+FlutamideEulexin®−−Folotyn®Pralatrexate±±FUDR®Floxuridine+±FulvestrantFaslodex®+−GefitinibIressa®−−Gemcitabine  HClGemzar®+−Gemtuzumab  ozogamicinMylotarg®±−Gemzar®Gemcitabine  HCl+−GilotrifAfatinib±±Gilotrif™Afatinib  dimaleate±±Gleevec®Imatinib  mesylate++Goserelin  acetateZoladex®−−Halaven™Eribulin  mesylate++Halotestin®Fluoxymesterone−+Herceptin®Trastuzumab−−Hexalen®Altretamine−−Hycamtin®Topotecan  HCl−+HydroxyureaDroxia®±+Ibritumomab  tiuxetanZevalin®−−IbrutinibImbruvica+−Iclusig™Ponatinib±±Idamycin®Idarubicin  HCl++Idarubicin  HClIdamycin®++Ifex®Ifosfamide±+IfosfamideIfex®±+Imatinib  mesylateGleevec®++ImbruvicaIbrutinib+−Interferon  alfa-2bIntron®  A−−Inlyta®Axitinib±±Intron®  AInterferon  alfa-2b−−IpilimumabYervoy™−−Iressa®Gefitinib−−IrinotecanCamptosar®+−IsotretinoinSotret®±−Istodax®Romidepsin±±IxabepiloneIxempra®+±Ixempra®Ixabepilone+±Jevtana®Cabazitaxel±±Kadcyla™ado-trastuzumab  emtansine±±Kyprolis™Carfilzomib±±LapatinibTykerb®+−LenalidomideRevlimid®−+LetrozoleFemara®+−Leucovorin  calciumLeucovorin−−LeucovorinLeucovorin  calcium−−Leukeran®Chlorambucil±+Leukine®Sargramostim−−Leuprolide  acetateLupron  Depot®−−Leustatin®Cladribine±+LomustineCeeNU®±+Lupron  Depot®Leuprolide  acetate−−Lysodren®Mitotane−−Marqibo®Vincristine  sulfate  liposome±±Matulane®Procarbazine  HCl−+Mechlorethamine  HClMustargen®−−Megace®Megestrol  acetate−−Megestrol  acetateMegace®−−MekinistTramtetinib±±Mekinist™Trametinib  dimethyl  sulfoxide±±Melphalan  (or  Melphalan  HCl)Alkeran®−+MercaptopurinePurinethol®±+MesnaMesnex®±±Mesnex®Mesna±±MethotrexateMethotrexate++MethotrexateMethotrexate++MitomycinMitozytrex®±+MitotaneLysodren®−−Mitoxantrone  HClNovantrone®±−Mitozytrex®Mitomycin±+Mozobil®Plerixafor−+Mustargen®Mechlorethamine  HCl−−Mylotarg®Gemtuzumab  ozogamicin±−Navelbine®Vinorelbine  tartrate+−NelarabineArranon®±±Neulasta®Pegfilgrastim±−Neumega®Oprelvekin−+Neupogen®Filgrastim−−NeutrexinTrimetrexate  glucuronate±−Nexavar®Sorafenib  tosylate−−Nilandron®Nilutamide+−NilotinibTasigna®+−NilutamideNilandron®+−Nipent®Pentostatin−±Novantrone®Mitoxantrone  HCl±−Nplate®Romiplostim±±ObinutuzumabGazyva±±Octreotide  acetateSandostatin®  LAR®++OfatumumabArzerra™−−Omacetaxine  mepesuccinateSynribo™±±Oncaspar®Pegaspargase−−Oncovin®Vincristine  sulfate+−Ontak®Denileukin  diftitox−−OprelvekinNeumega®−+OxaliplatinEloxatin®−+PaclitaxelTaxol®+−Paclitaxel  protein  bound  particlesAbraxane®+−Pamidronate  disodiumAredia®±+PanitumumabVectibix®−−Panretin®Alitretinoin−−Paraplatin−AQ®Carboplatin−+Pazopanib  HClVotrient™+−PegaspargaseOncaspar®−−PegfilgrastimNeulasta®±−Pemetrexed  disodiumAlimta®−±PentostatinNipent®−±Perjeta®Pertuzumab±±PertuzumabPerjeta®±±Platinol®Cisplatin−+PlerixaforMozobil®−+PomalidomidePomalyst®±±Pomalyst®Pomalidomide±±Ponatinib  HClIclusig™±±PralatrexateFolotyn®±±Procarbazine  HClMatulane®−+Procrit®Epoetin  Alfa−−Proleukin®Aldesleukin−+Provenge®Sipuleucel-T−−Purinethol®Mercaptopurine±+Raloxifene  HClEvista®±±RaltitrexedTomudex®−+RegorafenibStivarga®±±Revlimid®Lenalidomide−+Rituxan®Rituximab−−RituximabRituxan®−−RomidepsinIstodax®±±RomiplostimNplate®±±Sandostatin®  LAR®Octreotide  acetate++SargramostimLeukine®−−Savene™Dexrazoxane  HCl−−Sipuleucel-TProvenge®−−Stivarga®Regorafenib±±Soltamox™Tamoxifen  citrate−−Sorafenib  tosylateNexavar®−−Sotret®Isotretinoin±−Sprycel®Dasatinib±±StreptozocinZanosar®+−Sunitinib  malateSutent®±±Suprefact®Buserelin  acetate−−Sutent®Sunitinib  malate±±Synribo™Omacetaxine  mepesuccinate±±Tabloid®Thioguanine±−TafinlarDabrafenib±±Tafinlar®Dabrafenib  mesylate±±Tamoxifen  citrateSoltamox™−−Tarceva®Erlotinib  HCl+−Targretin®Bexarotene±±Tasigna®Nilotinib+−Taxol®Paclitaxel+−Taxotere®Docetaxel+−Tegafur-uracilUftoral®±−Temodar®Temozolomide±±TemozolomideTemodar®±±TemsirolimusTorisel®+−TeniposideVumon®±±ThalidomideThalomid®−−Thalomid®Thalidomide−−ThioguanineTabloid®±−Thiolex®Thiotepa±−ThiotepaThiolex®±−Tomudex®Raltitrexed−+Topotecan  HClHycamtin®−+Toremifene  citrateFareston®−−Torisel®Temsirolimus+−TositumomabBexxar®−±Totect®Dexrazoxane  HCl−+TrabectedinYondelis®±+Trametinib  dimethyl  sulfoxideMekinist™±±TramtetinibMekinist±±TrastuzumabHerceptin®−−Treanda®Bendamustine  HCl++TretinoinAtralin™++Trimetrexate  glucuronateNeutrexin±−Trisenox™Arsenic  trioxide++Tykerb®Lapatinib+−Uftoral®Tegafur-uracil±−ValrubicinValstar®−−Valstar®Valrubicin−−VandetanibCaprelsa®±+Vectibix®Panitumumab−−Velban®Vinblastine  sulfate+−Velcade®Bortezomib+±VemurafenibZelboraf®±±VePesid®Etoposide++Vidaza®Azacitidine++Vinblastine  sulfateVelban®+−Vincristine  sulfateOncovin®+−Vincristine  sulfate  liposomeMarqibo®±±Vinorelbine  tartrateNavelbine®+−VismodegibErivedge®±±VorinostatZolinza®+−Votrient™Pazopanib  HCl+−Vumon®Teniposide±±Xalkori®Crizotinib±±Xeloda®Capecitabine±+Xgeva®Denosumab±±Xtandi®Enzalutamide±±Yervoy™Ipilimumab−−Yondelis®Trabectedin±+Zaltrap®ziv-aflibercept±±Zanosar®Streptozocin+−Zelboraf®Vemurafenib±±Zevalin®Ibritumomab  tiuxetan−−Zinecard®Dexrazoxane  HCl−−ziv-afliberceptZaltrap®±±Zoladex®Goserelin  acetate−−Zoledronic  AcidZometa®±+Zolinza®Vorinostat+−Zometa®Zoledronic  Acid±+Zytiga®Abiraterone  acetate+−  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - hemonc.mhmedical.com/content.aspx?aid=1128367411
ER  -