TY - CHAP M1 - Book, Section TI - Hemolytic Anemia Resulting from a Chemical or Physical Agent A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. PY - 2017 T2 - Williams Manual of Hematology, 9e AB - Hemolysis can be mainly intravascular (ie, hypotonic lysis or heat damage) or predominantly extravascular (ie, arsine gas and oxygen).Certain drugs can induce hemolysis in individuals with abnormalities of erythrocytic enzymes, such as glucose-6-phosphate dehydrogenase, or with an unstable hemoglobin (see Chaps. 14 and 17). Such drugs can also cause hemolysis in normal individuals if given in sufficiently large doses.Other drugs induce hemolytic anemia through an immunologic mechanism (see Chap. 24).The drugs and chemicals discussed here cause hemolysis by other mechanisms. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1133362998 ER -