TY  - CHAP
M1  - Book, Section
TI  - Priapism in Sickle Cell Disease
A1  - MacDonald, Susan M.
A1  - Burnett, Arthur L.
A2  - Gladwin, Mark T.
A2  - Kato, Gregory J.
A2  - Novelli, Enrico M.
PY  - 2021
T2  - Sickle Cell Disease
AB  - Priapism  is  defined  as  a  prolonged  penile  erection,  either  long  beyond  sexual  stimulation  or,  more  typically,  unrelated  to  sexual  stimulation  or  interest.1  The  condition  is  relatively  uncommon,  with  a  reported  incidence  of  0.34  to  1.5  cases  per  100,000  male  patients  per  year.2,3  Estimations  of  incidence  are  likely  to  vary  by  region,  however,  because  the  proportion  of  the  population  with  sickle  cell  disease  or  sickle  cell  trait  will  vary.  Although  priapism  has  many  causes,  the  lifetime  risk  of  a  patient  with  sickle  cell  disease  developing  an  episode  of  priapism  is  between  29%  and  42%.4  In  the  United  States,  using  the  Nationwide  Emergency  Department  Sample,  Stein  et  al5  estimated  a  total  of  9991  encounters  per  year,  with  27.9%  of  these  encounters  leading  to  admission.  They  estimated  a  total  cost  of  $123,860,432  dollars  per  year  in  the  United  States  for  treatment  related  to  priapism,  with  86.8%  of  these  charges  stemming  from  inpatient  admission.5  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - hemonc.mhmedical.com/content.aspx?aid=1179344636
ER  -