TY - CHAP M1 - Book, Section TI - Amyloidosis A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Linch, David C. PY - 2022 T2 - Williams Manual of Hematology, 10e AB - Amyloidosis is a heterogeneous group of diseases characterized by tissue infiltration with misfolded protein precursors.The term amyloid is used to describe a substance with a homogeneous eosinophilic appearance by light microscopy when stained with hematoxylin and eosin, a green birefringence on polarizing light microscopy, and a characteristic β-pleated sheet appearance by x-ray diffraction.Nomenclature for the type of amyloidosis is with an “A” followed by the abbreviation of the name of the subunit protein.Some types of amyloidosis along with their sites of organ involvement are listed in Table 72–1. Clinicians are more likely to see patients with immunoglobulin light chain (AL), although other types are clinically important. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - hemonc.mhmedical.com/content.aspx?aid=1189335934 ER -