RT Book, Section
A1 Rezvani, Andrew R.
A1 Lowsky, Robert
A1 Negrin, Robert S.
A2 Kaushansky, Kenneth
A2 Lichtman, Marshall A.
A2 Prchal, Josef T.
A2 Levi, Marcel M.
A2 Press, Oliver W.
A2 Burns, Linda J.
A2 Caligiuri, Michael
SR Print(0)
ID 1121090627
T1 Hematopoietic Cell Transplantation
T2 Williams Hematology, 9e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071833004
LK hemonc.mhmedical.com/content.aspx?aid=1121090627
RD 2024/04/16
AB SUMMARYOver  the  past  60  years,  the  field  of  hematopoietic  cell  transplantation  (HCT)  has  evolved  from  experimental  animal  models  of  marrow  transplantation  to  curative  therapy  for  tens  of  thousands  of  people  yearly  who  are  affected  by  a  wide  variety  of  marrow  failure  states,  myeloid  and  lymphoid  malignancies,  immune  deficiencies,  and  inborn  errors  of  metabolism.  Advances  in  transplantation  immune  biology  combined  with  improvements  in  supportive  care  have  made  this  evolution  possible  and  have  ushered  in  the  modern  era  of  HCT.  This  chapter  discusses  the  biologic  principles  and  clinical  applications  of  HCT  along  with  its  future  applications.  Selected  results  demonstrating  important  principles  are  highlighted.