RT Book, Section A1 Witgert, Mariana E. A1 Wefel, Jeffrey S. A2 Duffy, James D. A2 Valentine, Alan D. SR Print(0) ID 1125785760 T1 Neurobehavioral Side Effects of Cancer and Cancer Therapy T2 MD Anderson Manual of Psychosocial Oncology YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071624381 LK hemonc.mhmedical.com/content.aspx?aid=1125785760 RD 2024/04/24 AB Advances in multimodal therapy have resulted in increased success in the management of many cancers. However, as many anticancer therapies are not highly specific, healthy tissues are also placed at risk. While traditional measures of treatment outcome have generally focused on survival time, progression-free survival, tumor response, and physiological toxicities, additional indices, including cognitive functioning and quality of life, are receiving increasing recognition as important and viable clinical endpoints. The following chapter presents evidence regarding the presence and nature of cancer- and treatment-related neurobehavioral symptoms in adult cancer patients as well as information regarding the interventions that are currently being employed against those side effects.