RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Kipps, Thomas J.
A1 Prchal, Josef T.
A1 Levi, Marcel M.
SR Print(0)
ID 1126651720
T1 Cryopathic Hemolytic Anemia
T2 Williams Manual of Hematology, 8e
YR 2011
FD 2011
PB McGraw-Hill Education
PP New York, NY
SN 9780071622424
LK hemonc.mhmedical.com/content.aspx?aid=1126651720
RD 2024/04/25
AB Caused  by  autoantibodies  that  bind  red  cells  best  at  temperatures  below  37°C,  usually  below  31°C.Mediated  through  two  major  types  of  "cold  antibody":  cold  agglutinins  and  Donath-Landsteiner  antibodies.Clinical  features  vary  considerably,  but  in  both  types,  the  complement  system  plays  a  major  role  in  red  cell  destruction.