RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Kipps, Thomas J.
A1 Prchal, Josef T.
A1 Levi, Marcel M.
SR Print(0)
ID 1126651876
T1 Polyclonal Polycythemias (Primary and Secondary)
T2 Williams Manual of Hematology, 8e
YR 2011
FD 2011
PB McGraw-Hill Education
PP New York, NY
SN 9780071622424
LK hemonc.mhmedical.com/content.aspx?aid=1126651876
RD 2024/04/16
AB Polycythemia  (also  known  as  erythrocytosis)  is  characterized  by  an  increased  red  cell  blood  volume.  Polycythemias  can  be  primary  or  secondary  and  either  inherited  or  acquired.Classification  of  polycythemic  disorders  appears  in  Table  2–2  in  Chap.  2.Primary  polycythemias  are  caused  by  somatic  or  germline  mutations  causing  changes  within  hematopoietic  stem  cells  or  erythroid  progenitors  causing  an  augmented  response  to  erythropoietin.Secondary  polycythemias  are  caused  by  either  an  appropriate  or  inappropriate  increase  in  the  red  cell  mass  as  a  result  of  augmented  levels  of  erythropoietin.