RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Kipps, Thomas J. A1 Prchal, Josef T. A1 Levi, Marcel M. SR Print(0) ID 1126653190 T1 The Mononucleosis Syndromes T2 Williams Manual of Hematology, 8e YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780071622424 LK hemonc.mhmedical.com/content.aspx?aid=1126653190 RD 2024/04/19 AB Infectious mononucleosis is defined as any blood lymphocytosis induced in response to an infectious agent.Usually greater than 50 percent of the circulating white cells are lymphocytes, more than 10 percent of which have the morphology of reactive lymphocytes (see Fig. 53–1).Table 53–1 lists the etiologic agents that produce mononucleosis.Pharyngeal form:— Sore throat preceded by 1 to 2 weeks of lethargy.— Epstein-Barr virus (EBV) generally is the cause.Glandular form without pharyngitis:— Lymph node enlargement.— Usually caused by agents other than EBV, e.g., Toxoplasma gondii.Typhoidal form:— Lethargy with fever or diarrhea without pharyngitis, usually as a consequence of cytomegalovirus (CMV).