RT Book, Section
A1 Tannock, Ian F.
A1 Hill, Richard P.
A1 Bristow, Robert G.
A1 Harrington, Lea
SR Print(0)
ID 1127462321
T1 Preface
T2 The Basic Science of Oncology, 5e
YR 2016
FD 2016
PB McGraw-Hill Education Medical
PP New York, NY
SN 9780071745208
LK hemonc.mhmedical.com/content.aspx?aid=1127462321
RD 2024/04/20
AB Since  the  publication  of  the  fourth  edition  of  The  Basic  Science  of  Oncology  there  have  been  major  advances  in  our  knowledge  about  the  molecular  basis  of  cancer,  largely  as  a  result  of  the  rapid  development  of  powerful  techniques  to  study  the  genome  and  epigenome  and  to  the  parallel  advances  in  techniques  to  study  the  levels  of  gene  expression  and  the  proteins  that  are  produced.  Concurrent  with  understanding  of  the  molecular  pathways  that  drive  the  development  and  progression  of  cancer,  and  the  heterogeneity  of  the  changes  in  these  pathways  in  individual  cancers,  new  molecular-targeted  agents  have  been  developed  and  are  being  tested,  with  variable  success,  in  attempts  to  treat  cancers  selectively.  The  5th  edition  of  The  Basic  Science  of  Oncology  places  the  major  advances  that  have  occurred  in  the  context  of  previous  studies  that  have  generated  the  important  background  to  cancer  biology.  Many  of  the  chapters  have  new  authors  and  all  have  been  extensively  revised  and  rewritten  to  reflect  our  new  knowledge.  We  have  added  new  chapters  on  the  emerging  areas  of  the  tumor  microenvironment  and  metabolism  (Chapter  12)  and  cancer  stem  cells  (Chapter  13).