RT Book, Section A1 Jaffray, David A. A2 Tannock, Ian F. A2 Hill, Richard P. A2 Bristow, Robert G. A2 Harrington, Lea SR Print(0) ID 1127472757 T1 Imaging in Oncology T2 The Basic Science of Oncology, 5e YR 2016 FD 2016 PB McGraw-Hill Education Medical PP New York, NY SN 9780071745208 LK hemonc.mhmedical.com/content.aspx?aid=1127472757 RD 2024/03/28 AB The need to detect and characterize cancer in an individual has resulted in a dramatic increase in the use of imaging over the last 20 years. Clinical imaging is now a routine part of diagnosis, staging, guiding localized therapy, and assessing response to treatment. Cancers occur anatomically among surrounding normal tissues, including critical structures, such as major vessels and nerves, and delineation of the extent of malignant and nonmalignant tissues is essential for planning surgery and radiation therapy. Cancers also have morphological, physiological, and biochemical heterogeneity (see Chaps. 10 and 12), which is important in understanding their biology and response to treatment. The ability to explore and define this heterogeneity with modern imaging methods, as well as serum and tissue-derived metrics, will enable "personalized cancer medicine."