RT Book, Section A1 Harding, Shane M. A1 Hill, Richard P. A1 Bristow, Robert G. A2 Tannock, Ian F. A2 Hill, Richard P. A2 Bristow, Robert G. A2 Harrington, Lea SR Print(0) ID 1127472876 T1 Molecular and Cellular Basis of Radiotherapy T2 The Basic Science of Oncology, 5e YR 2016 FD 2016 PB McGraw-Hill Education Medical PP New York, NY SN 9780071745208 LK hemonc.mhmedical.com/content.aspx?aid=1127472876 RD 2024/10/05 AB Since their discovery by Roentgen more than a century ago, x-rays have played a major role in modern medicine. The first recorded use of x-rays for the treatment of cancer occurred within 1 year of their discovery. Subsequently there has been intensive study of x-rays and other ionizing radiations, and their clinical application to cancer treatment has become increasingly sophisticated. This chapter and Chapter 16 review the biological effects of ionizing radiation and the application of that knowledge to cancer treatment.