RT Book, Section A1 Hilal-Dandan, Randa A1 Brunton, Laurence L. SR Print(0) ID 1127548738 T1 Pharmacotherapy of Psychosis and Mania T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071769174 LK hemonc.mhmedical.com/content.aspx?aid=1127548738 RD 2024/03/28 AB Psychosis is a symptom of mental illnesses characterized by a distorted or nonexistent sense of reality. Common psychotic disorders include mood disorders (major depression or mania) with psychotic features, substance-induced psychosis, dementia with psychotic features, delirium with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Schizophrenia has a worldwide prevalence of 1%, but patients with schizophrenia exhibit features that extend beyond those seen in other psychotic illnesses. The positive symptoms of psychotic disorders include: hallucinations, delusions, disorganized speech, and disorganized or agitated behavior. Schizophrenia patients also suffer from negative symptoms (apathy, avolition, alogia), and cognitive deficits, particularly deficits in working memory, processing speed, and social cognition.