RT Book, Section A1 Hilal-Dandan, Randa A1 Brunton, Laurence L. SR Print(0) ID 1127549304 T1 General Anesthetics and Therapeutic Gases T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071769174 LK hemonc.mhmedical.com/content.aspx?aid=1127549304 RD 2024/10/09 AB General anesthetics depress the central nervous system to a sufficient degree to permit the performance of surgery and unpleasant procedures. General anesthetics have low therapeutic indices and thus require great care in administration. The selection of specific drugs and routes of administration to produce general anesthesia is based on their pharmacokinetic properties and on the secondary effects of the various drugs, in the context of the proposed diagnostic or surgical procedure and with the consideration of the individual patient's age, and associated medical condition.