RT Book, Section
A1 Hilal-Dandan, Randa
A1 Brunton, Laurence L.
SR Print(0)
ID 1127550375
T1 Treatment of Myocardial Ischemia and Hypertension
T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071769174
LK hemonc.mhmedical.com/content.aspx?aid=1127550375
RD 2024/04/24
AB Angina  pectoris,  the  primary  symptom  of  ischemic  heart  disease,  is  caused  by  transient  episodes  of  myocardial  ischemia  that  are  due  to  an  imbalance  in  the  myocardial  oxygen  supply–demand  relationship  that  may  be  caused  by  an  increase  in  myocardial  oxygen  demand  or  by  a  decrease  in  myocardial  oxygen  supply  or  sometimes  by  both  (Figure  27–1).  Typical  angina  is  experienced  as  a  heavy,  pressing  substernal  discomfort  (rarely  described  as  a  "pain"),  often  radiating  to  the  left  shoulder,  flexor  aspect  of  the  left  arm,  jaw,  or  epigastrium.  However,  a  significant  minority  of  patients  note  discomfort  in  a  different  location  or  of  a  different  character.  Myocardial  ischemia  also  may  be  silent,  with  electrocardiographic,  echocardiographic,  or  radionuclide  evidence  of  ischemia  appearing  in  the  absence  of  symptoms.