RT Book, Section A1 Hilal-Dandan, Randa A1 Brunton, Laurence L. SR Print(0) ID 1127552196 T1 Androgens T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071769174 LK hemonc.mhmedical.com/content.aspx?aid=1127552196 RD 2024/10/04 AB In men, testosterone is the principal secreted androgen. Leydig cells synthesize the majority of testosterone by the pathways shown in Figure 41–1. In women, testosterone also is the principal androgen and is synthesized in the corpus luteum and the adrenal cortex by similar pathways. The testosterone precursors androstenedione and dehydroepiandrosterone are weak androgens that can be converted peripherally to testosterone.