RT Book, Section A1 Hilal-Dandan, Randa A1 Brunton, Laurence L. SR Print(0) ID 1127554293 T1 Antiviral Agents (Nonretroviral) T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071769174 LK hemonc.mhmedical.com/content.aspx?aid=1127554293 RD 2024/10/04 AB Viruses are simple microorganisms that consist of either double- or single-stranded DNA or RNA enclosed in a protein coat called a capsid. Some viruses also possess a lipid envelope derived from the infected host cell, which, like the capsid, may contain antigenic glycoproteins. Effective antiviral agents inhibit virus-specific replicative events or preferentially inhibit virus-directed rather than host cell–directed nucleic acid or protein synthesis (Table 58-1). Host cell molecules that are essential to viral replication also offer targets for intervention. Figure 58-1 gives a schematic diagram of the replicative cycle of typical DNA and RNA viruses.