RT Book, Section A1 Efstathiou, Jason A. A1 Gray, Phillip J. A1 Dahl, Douglas M. A2 Chabner, Bruce A. A2 Longo, Dan L. SR Print(0) ID 1127648570 T1 Localized Prostate Cancers T2 Harrison's Manual of Oncology, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071793254 LK hemonc.mhmedical.com/content.aspx?aid=1127648570 RD 2024/04/24 AB In the United States, an estimated 238,590 men will be diagnosed with prostate cancer in 2013 with 29,720 deaths attributable to prostate cancer (1). These statistics highlight a paradox of prostate cancer. Although it is the second leading cause of cancer death for men in the United States, only a relatively small percentage of men diagnosed with prostate cancer will die of their disease. This chapter will present guidelines for the management of localized prostate cancer. It will describe the controversies associated with prostate-specific antigen (PSA) screening, describe the work up and staging of prostate cancer, and finally discuss treatment options for localized disease.